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KMID : 0352419930120030330
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Keimyung Medical Journal
1993 Volume.12 No. 3 p.330 ~ p.336
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Proliferating Cell Nuclear Antigen in Breast Ductal Carcinoma
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Abstract
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39 cases of primary ductal carcinoma of breast surgically removed during the period 1990-1991 were investigated for the PCNA score, estrogen and progesterone receptors, histologic grade and clinical stage.
To determine the validity of these measurements, a variance analysis was done with Kruskal-wallis 1-way ANOVA. The results showed that PCNA has no statistical correlation with ER/PR status(P=0.25), clinical stage and histologic grade. PCNA score
increased with the mitotic rate increase. PCNA score has potential value as a prognostic indicator in breast ductal carcinoma and offers advantages of relative simplicity of method and applicability to paraffin-embedded section of formalin-fixed
tissue,
and low cost.
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KEYWORD
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